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Kucera, Gregory

One or more keywords matched the following items that are connected to Kucera, Gregory

Item Type	Name
Academic Article	Thermally inert metal ammines as light-inducible DNA-targeted agents. Synthesis, photochemistry, and photobiology of a prototypical rhodium(III)-intercalator conjugate.
Academic Article	A novel phospholipid gemcitabine conjugate is able to bypass three drug-resistance mechanisms.
Academic Article	Synthesis, biological activity, and DNA-damage profile of platinum-threading intercalator conjugates designed to target adenine.
Academic Article	Photoinduced cytotoxicity and thioadduct formation by a prodigiosin analogue.
Academic Article	A non-cross-linking platinum-acridine agent with potent activity in non-small-cell lung cancer.
Academic Article	Using a build-and-click approach for producing structural and functional diversity in DNA-targeted hybrid anticancer agents.
Academic Article	Effect of the diamine nonleaving group in platinum-acridinylthiourea conjugates on DNA damage and cytotoxicity.
Academic Article	Effect of linkage geometry on biological activity in thiourea- and guanidine-substituted acridines and platinum-acridines.
Academic Article	Gold(I) analogues of a platinum-acridine antitumor agent are only moderately cytotoxic but show potent activity against Mycobacterium tuberculosis.
Academic Article	Analysis of the DNA damage produced by a platinum-acridine antitumor agent and its effects in NCI-H460 lung cancer cells.
Concept	Drug Screening Assays, Antitumor
Academic Article	Redesigning the DNA-targeted chromophore in platinum-acridine anticancer agents: a structure-activity relationship study.
Academic Article	The novel phospholipid mimetic KPC34 is highly active against preclinical models of Philadelphia chromosome positive acute lymphoblastic leukemia.

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Drug Evaluation Preclinical